The Heckler & Koch HK45 USP Tactical is a semi-automatic pistol that was first introduced in 2006. The HK45 USP Tactical is based on the Heckler & Koch USP (Universal Self-loading Pistol), which was first introduced in 1993. 

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The HK45 USP Tactical is chambered for the .45 ACP cartridge. The HK45 USP Tactical features a polymer frame and a stainless steel slide, which makes it lightweight and durable. The HK45 USP Tactical also features a match-grade barrel, which improves accuracy and reduces recoil. The HK45 USP Tactical is equipped with a threaded barrel, which allows for the attachment of a suppressor. The HK45 USP Tactical also features a tactical rail, which allows for the attachment of accessories such as a laser sight or a flashlight. It also features an ambidextrous magazine release and slide stop, making it easy for left-handed shooters to use.

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The HK45 USP Tactical has been used by a number of law enforcement agencies and military units around the world. The HK45 USP Tactical was used by US Navy SEALs during Operation Neptune Spear, which resulted in the death of Osama bin Laden. The HK45 USP Tactical has also been used by the German military and by law enforcement agencies in the United States.